An estimate of how well your kidneys filter waste, using a routine blood creatinine test.
eGFR stands for estimated glomerular filtration rate. It is not measured directly but calculated, usually from your blood creatinine along with your age and sex, using the CKD-EPI equation.
It estimates how many millilitres of blood your kidneys filter each minute, and it is the standard way to summarise overall kidney function in a single number.
A lower eGFR means your kidneys are filtering less well. It is the main number used to stage chronic kidney disease, from G1 (normal) down to G5 (kidney failure). A result below 60 that lasts three months or more defines chronic kidney disease.
Because it is calculated from creatinine, the same limits apply. Muscle mass and diet can affect it, which is why a cystatin C based eGFR is sometimes used to confirm a result.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
| Stage | eGFR (mL/min/1.73m2) |
| G1 normal | 90 or above |
| G2 mildly reduced | 60 to 89 |
| G3a to G3b | 30 to 59 |
| G4 to G5 | below 30 |
Ranges follow KDIGO staging used in Germany. A normal eGFR with no other signs of kidney damage is reassuring. A value below 60 lasting three months or more defines chronic kidney disease. Read alongside your creatinine and urine tests.
Because it comes from creatinine, anything that affects creatinine affects eGFR. Very high or low muscle mass, a large meat meal, intense exercise, and some medicines can shift it. It is less reliable at near normal levels, where small changes mean little.
Best read with creatinine, cystatin C, and a urine albumin to creatinine ratio, which together stage kidney health.
What does my eGFR mean? Higher usually means kidneys filter well; lower suggests reduced filtering. Your clinician will check trends and related tests.
Do I need to fast for this test? No. Eat normally, but come well hydrated.
What can affect my result? Dehydration, hard exercise, a large cooked meat meal, creatine supplements, and some medicines can change readings.
How often should I test eGFR? At least yearly if you have risk factors. Your clinician may test more often to track changes.
How quickly will I get results? Results are usually ready in about 7 days.
What should I discuss with my clinician? Share all medicines and supplements, recent illness, pregnancy, and hydration. Ask about next steps like urine albumin or cystatin C.
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