A serum tube is a blood collection tube in which the blood is allowed to clot, so the clear liquid above the clot, called serum, can be measured. Many hormone, vitamin and blood fat values are measured from serum.
When blood clots in a serum tube, the cells and the clotting proteins form a solid part, and the clear yellow liquid left above it is serum. The laboratory spins the tube in a centrifuge to separate the two and then measures values such as cholesterol, vitamin D, ferritin and many hormones from the serum.
In a kit for home collection the serum tube is a small tube that fits onto the collection device, such as Tasso+. If the panel needs more serum than a tube holds, the kit carries a second tube or a second device.
For a buyer the tube type matters because a value measured from the wrong tube cannot be reported. Ask a supplier which tube each value in your panel needs and who decides which tubes go into each kit.
In this glossary, EDTA tube describes the other common tube, Haemolysis explains a common reason a serum sample fails, and Präanalytik covers everything that happens to a tube before analysis.
This glossary entry is general information, not medical advice, and it is not intended to diagnose, treat or rule out any condition. Discuss your own results with a clinician who knows your history.

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