A calculated score from fasting glucose and insulin that estimates how sensitive your body is to insulin.
QUICKI, the Quantitative Insulin Sensitivity Check Index, is a calculated index, not a separate blood test. It estimates how sensitive your body is to insulin from a single fasting blood sample.
The formula is: QUICKI = 1 ÷ (log fasting insulin in mU/L + log fasting glucose in mg/dL). A logarithmic transformation makes the index more even across the population.
When cells respond poorly to insulin, the body needs more of it to keep blood sugar normal. QUICKI combines fasting insulin and glucose into a single number that correlates well with more complex insulin sensitivity tests, giving an early read on metabolic health.
A lower QUICKI means lower insulin sensitivity, that is, more insulin resistance, which is linked with prediabetes, type 2 diabetes and cardiovascular risk. A higher value reflects better insulin sensitivity.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
Interpretive thresholds, which vary by population and insulin assay:
Cutoffs are not fully standardised and differ between labs, so read QUICKI as guidance with your clinician.
QUICKI needs a genuine fasting sample, since recent food raises insulin and glucose. Insulin assays are not standardised between labs, so absolute values should not be compared across providers. It is not valid in people treated with insulin and is less reliable in established diabetes.
Read with its components, fasting insulin and fasting glucose, and alongside HOMA-IR, HbA1c, triglycerides and HDL.
What does a QUICKI result mean? Higher scores suggest better insulin sensitivity; lower scores suggest reduced sensitivity. It adds context but isn’t used alone to diagnose.
Do I need to fast for this test? Yes. QUICKI uses fasting glucose and fasting insulin. Aim for 8 to 12 hours of water-only fasting unless told otherwise.
What can affect my result? Recent food or alcohol, heavy exercise, illness, stress, some medicines, and high-dose biotin can shift results. Try to test under consistent conditions.
How often should I test? Many people check every 3 to 6 months when monitoring lifestyle changes or risk. Your clinician may suggest a different interval.
How long do results take? Results are usually ready in about 7 days.
What should I discuss with my clinician? Review your QUICKI alongside glucose, HbA1c, and symptoms, and ask whether follow-up testing or lifestyle changes are appropriate.
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