GGT is a liver enzyme that helps flag bile duct stress and alcohol-related effects.
Gamma-glutamyl transferase (GGT) is an enzyme found in the liver and the bile ducts. It plays a role in moving certain molecules across cell membranes.
GGT rises when the liver or bile ducts are under strain, and it is especially sensitive to alcohol and to blocked bile flow.
A raised GGT often points to alcohol, fatty liver, certain medicines, or a problem with bile flow. It is sensitive but not very specific, so it is read alongside other liver markers.
GGT is particularly helpful for confirming that a raised alkaline phosphatase is coming from the liver rather than from bone, since GGT does not rise with bone conditions.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
| Group | Serum GGT (SI) |
| Men | up to ~60 U/L |
| Women | up to ~40 U/L |
Ranges are guidance only and vary by lab, assay, and sex. Read your result against your own lab's reference interval, in line with DGKL practice.
Alcohol in the days before the test can raise GGT, as can many medicines, including some used for seizures. Obesity and fatty liver push it up. Fasting is not required, but recent heavy drinking should be noted.
Best read with alkaline phosphatase (to locate a cholestasis pattern), and with ALT and AST for overall liver health.
What does a high GGT mean? It often signals bile duct irritation, liver stress, alcohol effects, or medicine effects. Your clinician will review it with other liver tests.
Do I need to fast for a GGT test? No. You do not need to fast, but avoiding alcohol before the test is helpful.
What can raise GGT besides liver disease? Alcohol, smoking, certain medicines, obesity, diabetes, thyroid issues, and recent illness can raise GGT.
How often should I test GGT? It depends on your situation. Many people recheck after changing alcohol use, medicines, or when other liver tests are abnormal.
How long do results take? Results are usually ready in about 7 days.
What should I discuss with my clinician? Share symptoms, all medicines and supplements, alcohol use, and results of other liver tests like ALT, AST, ALP, and bilirubin.
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