Shows the balance between albumin and globulins, giving clues about liver, kidney, hydration, and immune changes.
The albumin/globulin (A/G) ratio is a calculated value, not a separate blood test. It is total albumin divided by globulin, where globulin is worked out by subtracting albumin from total protein. It compares the two main groups of proteins in your blood.
The ratio helps tell apart different reasons for an abnormal total protein. A low A/G ratio can point to more globulins (such as in chronic inflammation, infection, liver disease, or some blood cancers) or to low albumin. A high ratio is less common and is usually mild. The ratio is a screening clue, not a diagnosis on its own.
Aniva reads your result against research-backed ranges, not just the lab's wide normal. The reference shown below is specific to this biomarker.
These are interpretive guides, not strict lab ranges, and they vary by laboratory and method.
| A/G ratio | Interpretation |
|---|---|
| About 1.1 to 2.5 | Typically considered normal |
| Below ~1.1 | Low: review for raised globulins or low albumin |
| Above ~2.5 | High: usually mild, occasionally low globulin states |
Anything affecting albumin or total protein affects the ratio: dehydration, recent illness or inflammation, liver or kidney disease, and lying down versus standing during the draw. Globulin is a calculated figure, so errors in albumin or total protein carry through.
Best read with its components: albumin, total protein, and the calculated globulin, plus markers of inflammation and liver and kidney function.
What does my A/G ratio mean? It compares albumin to globulins. High or low values suggest shifts in liver function, immune activity, hydration, or protein loss.
Do I need to fast for this test? No. Fasting is not required for the albumin/globulin ratio.
What can affect my result? Dehydration, IV fluids, pregnancy, acute illness, hard exercise, and medicines like steroids, estrogen therapy, and diuretics can change the ratio.
How often should I test it? It’s usually checked with routine panels or to monitor changes. If abnormal, your clinician may recheck within weeks to months.
How long do results take? Results are usually ready in about 7 days.
What should I discuss with my clinician? Ask what might be driving a high or low ratio and whether to follow up with albumin, total protein, liver enzymes, or serum protein electrophoresis.
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